Developmental origins of non-communicable disease: Implications for research and public health

Developmental origins of non-communicable disease: Implications for research and public health

This White Paper highlights the developmental period as a plastic phase, which allows the organism to adapt to changes in the environment to maintain or improve reproductive capability in part through sustained health. Plasticity is more prominent prenatally and during early postnatal life, i.e., during the time of cell differentiation and specific tissue formation. These developmental periods ...

Developmental origins of obesity and non-communicable disease.

Developmental Origins of Health and Disease: A Lifecourse Approach to the Prevention of Non-Communicable Diseases

Non-communicable diseases (NCDs), such as cardiovascular disease and osteoporosis, affect individuals in all countries worldwide. Given the very high worldwide prevalence of NCDs across a range of human pathology, it is clear that traditional approaches targeting those at most risk in older adulthood will not efficiently ameliorate this growing burden. It will thus be essential to robustly iden...

Communicable Disease and Public Health

Current UK policy on immunisation for tetanus has changed in the light of evidence that five doses of vaccine probably provides sufficient protection as long as high-risk wounds are managed with tetanus immunoglobulin. This paper reviews the evidence base for tetanus immunisation policy in England and Wales: the epidemiology of tetanus, vaccination coverage and response to tetanus toxoid, and p...

Communicable Disease and Public Health

258 VOL 2 NO 4 DECEMBER 1999 Introduction Guidance on the risks and management of occupational exposure to hepatitis C was last issued in 1993 by the PHLS Hepatitis Subcommittee1. Since then, knowledge has increased about the prevalence of hepatitis C virus (HCV) infection in the United Kingdom (UK), the risks of occupational transmission, and the benefits of treatment. Guidance on the manageme...